Portland-OR Cruise Departures
Cruises that depart from North America: United States: Oregon: Portland-OR
See all River Cruises that depart from Portland-OR
8 Night - Columbia & Snake Rivers Cruise
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, Oct 30, 2027: Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, More...
8 Night - Columbia & Snake Rivers Cruise
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 3, May 17, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, More...
8 Night - Columbia & Snake Rivers Cruise
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 5, May 19, Jun 2, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Oct 6, Oct 20, Nov 3, 2027: Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, More...
8 Night - Columbia & Snake Rivers Cruise
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, Nov 6, 2027: Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, More...
8 Night - Columbia & Snake Rivers Cruise
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 10, May 24, Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, 2027: Apr 11, Apr 25, May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, More...
8 Night - Columbia & Snake Rivers Cruise
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 12, May 26, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, 2027: Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, More...15 Night - National Parks & Legendary Rivers
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River Gorge, Richland, WA, Cruising the Snake River / Clarkston, WA, Clarkston, WA to National Parks Adventure Begins, Glacier National Park, Travel Toward Yellowstone National Park, Yellowstone National Park, Yellowstone / Grand Teton National Park, Grand Teton National Park, Jackson, WY
2026 Sails: May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, 2027: May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, 2028: Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, More...15 Night - National Parks & Legendary Rivers
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River Gorge, Richland, WA, Cruising the Snake River / Clarkston, WA, Clarkston, WA to National Parks Adventure Begins, Glacier National Park, Travel Toward Yellowstone National Park, Yellowstone National Park, Yellowstone / Grand Teton National Park, Grand Teton National Park, Jackson, WY
2026 Sails: Jun 6, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, More...15 Night - National Parks & Legendary Rivers
Starting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River Gorge, Richland, WA, Cruising the Snake River / Clarkston, WA, Clarkston, WA to National Parks Adventure Begins, Glacier National Park, Travel Toward Yellowstone National Park, Yellowstone National Park, Yellowstone / Grand Teton National Park, Grand Teton National Park, Jackson, WY
2026 Sails: Jun 9, Jul 21, Aug 4, Aug 18, 2027: Jun 8, Jul 20, Aug 3, Aug 17, More...
7 Night - Columbia and Snake Rivers : Food, Wine and History
Starting in Portland-OR / Embark Ship, Astoria, Cruising / The Dalles / Hood River, Walla Walla, Washington, Palouse River, Clarkston, Clarkston / Disembark Ship
2026 Sails: Sep 5, Sep 19, Oct 3, Oct 17, More...
Cruises that depart from North America: United States: Oregon: Portland-OR
See all River Cruises that depart from Portland-OR
Click on a cruise ship itinerary sailing from Portland-OR (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portland-OR), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - Columbia & Snake Rivers CruiseStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, Oct 30, 2027: Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, More...
8 Night - Columbia & Snake Rivers CruiseStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 3, May 17, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, More...
8 Night - Columbia & Snake Rivers CruiseStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 5, May 19, Jun 2, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Oct 6, Oct 20, Nov 3, 2027: Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, More...
8 Night - Columbia & Snake Rivers CruiseStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, Nov 6, 2027: Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, More...
8 Night - Columbia & Snake Rivers CruiseStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 10, May 24, Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, 2027: Apr 11, Apr 25, May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, More...
8 Night - Columbia & Snake Rivers CruiseStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River, Pendleton, OR / Richland, WA, Clarkston, WA
2026 Sails: May 12, May 26, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, 2027: Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, More...
15 Night - National Parks & Legendary RiversStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River Gorge, Richland, WA, Cruising the Snake River / Clarkston, WA, Clarkston, WA to National Parks Adventure Begins, Glacier National Park, Travel Toward Yellowstone National Park, Yellowstone National Park, Yellowstone / Grand Teton National Park, Grand Teton National Park, Jackson, WY
2026 Sails: May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, 2027: May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, 2028: Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, More...
15 Night - National Parks & Legendary RiversStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River Gorge, Richland, WA, Cruising the Snake River / Clarkston, WA, Clarkston, WA to National Parks Adventure Begins, Glacier National Park, Travel Toward Yellowstone National Park, Yellowstone National Park, Yellowstone / Grand Teton National Park, Grand Teton National Park, Jackson, WY
2026 Sails: Jun 6, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, More...
15 Night - National Parks & Legendary RiversStarting in Portland-OR, Cruising the Columbia River, Astoria, Or, Kalama, WA, The Dalles, OR, Cruising the Columbia River Gorge, Richland, WA, Cruising the Snake River / Clarkston, WA, Clarkston, WA to National Parks Adventure Begins, Glacier National Park, Travel Toward Yellowstone National Park, Yellowstone National Park, Yellowstone / Grand Teton National Park, Grand Teton National Park, Jackson, WY
2026 Sails: Jun 9, Jul 21, Aug 4, Aug 18, 2027: Jun 8, Jul 20, Aug 3, Aug 17, More...
7 Night - Columbia and Snake Rivers : Food, Wine and HistoryStarting in Portland-OR / Embark Ship, Astoria, Cruising / The Dalles / Hood River, Walla Walla, Washington, Palouse River, Clarkston, Clarkston / Disembark Ship
2026 Sails: Sep 5, Sep 19, Oct 3, Oct 17, More...
